ATC code G03

ATC codes

G Genito-urinary system and sex hormones

G01 Gynecological antiinfectives and antiseptics

G02 Other gynecologicals

G03 Sex hormones and modulators of the genital system

G04 Urologicals

ATCvet only

QG51 Antiinfectives and antiseptics for intrauterine use

QG52 Products for teats and udder

ATC code G03 Sex hormones and modulators of the genital system is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the WHO for the classification of drugs and other medical products. Subgroup G03 is part of the anatomical group G Genito-urinary system and sex hormones.^[1]

Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QG03.^[2] ATCvet codes without corresponding human ATC codes are cited with the leading Q in the following list.

National issues of the ATC classification may include additional codes not present in this list, which follows the WHO version.

G03A Hormonal contraceptives for systemic use

G03AA Progestogens and estrogens, fixed combinations

G03AA01 Etynodiol and ethinylestradiol

G03AA02 Quingestanol and ethinylestradiol

G03AA03 Lynestrenol and ethinylestradiol

G03AA04 Megestrol and ethinylestradiol

G03AA05 Norethisterone and ethinylestradiol

G03AA06 Norgestrel and ethinylestradiol

G03AA07 Levonorgestrel and ethinylestradiol

G03AA08 Medroxyprogesterone and ethinylestradiol

G03AA09 Desogestrel and ethinylestradiol

G03AA10 Gestodene and ethinylestradiol

G03AA11 Norgestimate and ethinylestradiol

G03AA12 Drospirenone and ethinylestradiol

G03AA13 Norelgestromin and ethinylestradiol

G03AA14 Nomegestrol and estradiol

G03AA15 Chlormadinone and ethinylestradiol

G03AA16 Dienogest and ethinylestradiol

G03AB Progestogens and estrogens, sequential preparations

G03AB01 Megestrol and ethinylestradiol

G03AB02 Lynestrenol and ethinylestradiol

G03AB03 Levonorgestrel and ethinylestradiol

G03AB04 Norethisterone and ethinylestradiol

G03AB05 Desogestrel and ethinylestradiol

G03AB06 Gestodene and ethinylestradiol

G03AB07 Chlormadinone and ethinylestradiol

G03AB08 Dienogest and estradiol

G03AC Progestogens

G03AC01 Norethisterone

G03AC02 Lynestrenol

G03AC03 Levonorgestrel

G03AC04 Quingestanol

G03AC05 Megestrol

G03AC06 Medroxyprogesterone

G03AC07 Norgestrienone

G03AC08 Etonogestrel

G03AC09 Desogestrel

G03AC10 Drospirenone

G03AD Emergency contraceptives

G03AD01 Levonorgestrel

G03AD02 Ulipristal

G03B Androgens

G03BA 3-oxoandrosten-(4) derivatives

G03BA01 Fluoxymesterone

G03BA02 Methyltestosterone

G03BA03 Testosterone

G03BB 5-androstanon-(3) derivatives

G03BB01 Mesterolone

G03BB02 Androstanolone

G03C Estrogens

G03CA Natural and semisynthetic estrogens, plain

G03CA01 Ethinylestradiol

G03CA03 Estradiol

G03CA04 Estriol

G03CA06 Chlorotrianisene

G03CA07 Estrone

G03CA09 Promestriene

G03CA53 Estradiol, combinations

G03CA57 Conjugated estrogens

G03CB Synthetic estrogens, plain

G03CB01 Dienestrol

G03CB02 Diethylstilbestrol

G03CB03 Methallenestril

G03CB04 Moxestrol

G03CC Estrogens, combinations with other drugs

G03CC02 Dienestrol

G03CC03 Methallenestril

G03CC04 Estrone

G03CC05 Diethylstilbestrol

G03CC06 Estriol

G03CC07 Conjugated estrogens and bazedoxifene

G03CX Other estrogens

G03CX01 Tibolone

G03D Progestogens

G03DA Pregnen-(4) derivatives

G03DA01 Gestonorone

G03DA02 Medroxyprogesterone

G03DA03 Hydroxyprogesterone

G03DA04 Progesterone

QG03DA90 Proligeston

G03DB Pregnadien derivatives

G03DB01 Dydrogesterone

G03DB02 Megestrol

G03DB03 Medrogestone

G03DB04 Nomegestrol

G03DB05 Demegestone

G03DB06 Chlormadinone

G03DB07 Promegestone

G03DB08 Dienogest

G03DC Estren derivatives

G03DC01 Allylestrenol

G03DC02 Norethisterone

G03DC03 Lynestrenol

G03DC04 Ethisterone

G03DC06 Etynodiol

G03DC31 Methylestrenolone

QG03DX Other progestogens

QG03DX90 Altrenogest

QG03DX91 Delmadinone

G03E Androgens and female sex hormones in combination

G03EA Androgens and estrogens

G03EA01 Methyltestosterone and estrogen

G03EA02 Testosterone and estrogen

G03EA03 Prasterone and estrogen

G03EK Androgens and female sex hormones in combination with other drugs

G03EK01 Methyltestosterone

G03F Progestogens and estrogens in combination

G03FA Progestogens and estrogens, fixed combinations

G03FA01 Norethisterone and estrogen

G03FA02 Hydroxyprogesterone and estrogen

G03FA03 Ethisterone and estrogen

G03FA04 Progesterone and estrogen

G03FA05 Methylnortestosterone and estrogen

G03FA06 Etynodiol and estrogen

G03FA07 Lynestrenol and estrogen

G03FA08 Megestrol and estrogen

G03FA09 Noretynodrel and estrogen

G03FA10 Norgestrel and estrogen

G03FA11 Levonorgestrel and estrogen

G03FA12 Medroxyprogesterone and estrogen

G03FA13 Norgestimate and estrogen

G03FA14 Dydrogesterone and estrogen

G03FA15 Dienogest and estrogen

G03FA16 Trimegestone and estrogen

G03FA17 Drospirenone and estrogen

G03FB Progestogens and estrogens, sequential preparations

G03FB01 Norgestrel and estrogen

G03FB02 Lynestrenol and estrogen

G03FB03 Chlormadinone and estrogen

G03FB04 Megestrol and estrogen

G03FB05 Norethisterone and estrogen

G03FB06 Medroxyprogesterone and estrogen

G03FB07 Medrogestone and estrogen

G03FB08 Dydrogesterone and estrogen

G03FB09 Levonorgestrel and estrogen

G03FB10 Desogestrel and estrogen

G03FB11 Trimegestone and estrogen

G03FB12 Nomegestrol and estrogen

G03G Gonadotropins and other ovulation stimulants

G03GA Gonadotropins

G03GA01 Human chorionic gonadotropin

G03GA02 Human menopausal gonadotropin

G03GA03 Serum gonadotropin

G03GA04 Urofollitropin

G03GA05 Follitropin alfa

G03GA06 Follitropin beta

G03GA07 Lutropin alfa

G03GA08 Choriogonadotropin alfa

G03GA09 Corifollitropin alfa

G03GA30 Combinations

QG03GA90 Follicle stimulating hormone-pituitary

QG03GA99 Gonadotropins, combinations

G03GB Ovulation stimulants, synthetic

G03GB01 Cyclofenil

G03GB02 Clomifene

G03GB03 Epimestrol

G03H Antiandrogens

G03HA Antiandrogens, plain

G03HA01 Cyproterone

G03HB Antiandrogens and estrogens

G03HB01 Cyproterone and estrogen

G03X Other sex hormones and modulators of the genital system

G03XA Antigonadotropins and similar agents

G03XA01 Danazol

G03XA02 Gestrinone

QG03XA90 Anti-Pmsg

QG03XA91 Gonadotropin releasing factor analogue, conjugated

G03XB Progesterone receptor modulators

G03XB01 Mifepristone

G03XB02 Ulipristal

G03XB51 Mifepristone, combinations

QG03XB90 Aglepristone

G03XC Selective estrogen receptor modulators

G03XC01 Raloxifene

G03XC02 Bazedoxifene

G03XC03 Lasofoxifene

G03XC04 Ormeloxifene

G03XC05 Ospemifene

References

↑ "ATC/DDD Index 2016: code G03". WHO Collaborating Centre for Drug Statistics Methodology.
↑ "ATCvet Index 2016: code QG03". WHO Collaborating Centre for Drug Statistics Methodology.

Birth control methods (G02B, G03A)

Comparison

Behavioral

Avoiding vaginal intercourse: Abstinence
Anal sex
Masturbation
Non-penetrative sex
Oral sex
Including vaginal intercourse: Breastfeeding infertility (LAM)
Calendar-based methods (rhythm, etc.)
Fertility awareness (Billings ovulation method
Creighton Model, etc.)
Withdrawal

Barrier and / or
spermicidal

Hormonal
(formulations)

Combined	Contraceptive patch Extended cycle Injectable NuvaRing Oral / 'the pill'

Progestogen-only	LARC (Depo-Provera Implanon/Nexplanon Norplant/Jadelle) Progestogen-only pill / 'minipill'

Anti-estrogen

Ormeloxifene (Centchroman)

Post-intercourse

Emergency contraception (pills or copper IUD) (Ulipristal acetate
Yuzpe regimen)

Intrauterine device

IUD with copper
- Paragard
IUD with progestogen (Mirena)

Abortion

Medical (RU-486/abortion pill)
Surgical

Sterilization

Female: Essure
Tubal ligation
Male: Vasectomy

Experimental

Reversible inhibition of sperm under guidance (Vasalgel)

Androgens and antiandrogens

Androgens
(incl. AAS)

AR agonists	Testosterone derivatives: Boldenone undecylenate Clostebol Clostebol acetate Clostebol caproate Clostebol propionate Cloxotestosterone acetate Dehydroepiandrosterone (DHEA) (androstenolone, prasterone) DHEA enanthate (prasterone enanthate) Quinbolone Testosterone^# Testosterone acetate Testosterone capropate Testosterone cyclohexylpropionate Testosterone cypionate Testosterone decanoate Testosterone enanthate Testosterone ester mixtures (Deposterona, Omnadren, Sustanon) Testosterone furoate Testosterone hexahydrobenzoate Testosterone hexahydrobenzylcarbonate Testosterone hexyloxyphenylpropionate Testosterone isobutyrate Testosterone isocaproate Testosterone ketolaurate Testosterone nicotinate Testosterone phenylacetate Testosterone phenylpropionate Testosterone phosphate Testosterone propionate Testosterone undecanoate Testosterone valerate Dihydrotestosterone derivatives: Bolazine capronate Dihydrotestosterone (DHT) (androstanolone, stanolone) Dihydrotestosterone acetate Dihydrotestosterone benzoate Dihydrotestosterone butyrate Dihydrotestosterone enanthate Dihydrotestosterone formate Dihydrotestosterone propionate Dihydrotestosterone valerate Drostanolone propionate (dromostanolone propionate) Epitiostanol Mepitiostane Mesterolone Metenolone acetate (methenolone acetate) Metenolone enanthate (methenolone enanthate) Stenbolone acetate 19-Nortestosterone derivatives: Bolandiol dipropionate Nandrolone caproate Nandrolone cypionate Nandrolone cyclohexanecarboxylate Nandrolone cyclohexylpropionate Nandrolone decanoate Nandrolone furylpropionate Nandrolone hexyloxyphenylpropionate Nandrolone hydrogen succinate Nandrolone laurate Nandrolone phenylpropionate Nandrolone propionate Nandrolone sulfate sodium Nandrolone undecanoate Norclostebol Norclostebol acetate Oxabolone cipionate (oxabolone cypionate) Trenbolone acetate Trenbolone hexahydrobenzylcarbonate (trenbolone cyclohexylmethylcarbonate) 17α-Alkylated testosterone derivatives: Bolasterone Calusterone Chlorodehydromethyltestosterone (CDMT) Fluoxymesterone Formebolone Metandienone (methandienone, methandrostenolone) Methandriol (methylandrostenediol) Methandriol bisenanthoyl acetate Methandriol dipropionate Methandriol propionate Methyltestosterone Oxymesterone Penmesterol Tiomesterone (thiomesterone) 17α-Alkylated dihydrotestosterone derivatives: Androisoxazole Furazabol Mebolazine (dimethazine) Mestanolone Oxandrolone Oxymetholone Stanozolol 17α-Alkylated 19-nortestosterone derivatives: Ethylestrenol Mibolerone Norethandrolone Normethandrone (methylestrenolone, normethisterone) Propetandrol (propethandrol) 17α-Vinyltestosterone derivatives: Norvinisterone (vinylnortestosterone) 17α-Ethynyltestosterone derivatives: Danazol Gestrinone Progestins (e.g., ethisterone (ethynyltestosterone), levonorgestrel, norgestrel, norethisterone (norethindrone), lynestrenol, norgestrienone) Tibolone Progesterone derivatives: Medroxyprogesterone acetate

Progonadotropins	Antiestrogens (e.g., tamoxifen, clomifene) GnRH agonists (e.g., GnRH (gonadorelin), leuprorelin) Gonadotropins (e.g., LH, hCG)

Antiandrogens

AR antagonists

Steroidogenesis
inhibitors

5α-Reductase	Alfatradiol Dutasteride Epristeride Finasteride Saw palmetto extract

Others	Abiraterone acetate Aminoglutethimide Bifluranol Cyproterone acetate Flutamide Ketoconazole Nilutamide Seviteronel^† Spironolactone

Antigonadotropins

D₂ receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
Estrogens (e.g., bifluranol, diethylstilbestrol, estradiol, estradiol esters, ethinyl estradiol, ethinyl estradiol sulfonate, paroxypropione)
GnRH agonists (e.g., leuprorelin)
GnRH antagonists (e.g., cetrorelix)
Progestogens (incl., chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate)

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

See also: Estrogens and antiestrogens • Progestogens and antiprogestogens • Glucocorticoids and antiglucocorticoids • Mineralocorticoids and antimineralocorticoids • Gonadotropins and GnRH

Estrogens and antiestrogens

Estrogens

ER agonists	Steroidal: Alfatradiol Certain androgenic-anabolic steroids (e.g., testosterone, testosterone esters, nandrolone, methyltestosterone, metandienone) (via estrogenic metabolites) Certain progestins (e.g., norethisterone, noretynodrel, etynodiol diacetate, tibolone) Clomestrone Cloxestradiol acetate Conjugated equine estrogens/esterified estrogens (Premarin) 8,9-Dehydroestrone sulfate 17α-Dihydroequilenin sulfate 17α-Dihydroequilin sulfate 17β-Dihydroequilenin sulfate 17β-Dihydroequilin sulfate Equilenin sulfate Equilin sulfate Epiestriol Epimestrol Estetrol^† Estradiol Estradiol acetate Estradiol benzoate Estradiol butyrylacetate Estradiol cypionate^# Estradiol dienanthate Estradiol dipropionate Estradiol diundecylate Estradiol diundecylenate Estradiol enanthate Estradiol furoate Estradiol hemihydrate Estradiol hemisuccinate (estradiol succinate) Estradiol hexahydrobenzoate Estradiol monopropionate Estradiol palmitate Estradiol phenylpropionate Estradiol pivalate (trimethyl estradiol acetate) Estradiol propoxyphenylpropionate Estradiol stearate Estradiol undecylate Estradiol valerate Polyestradiol phosphate Estramustine Estriol Estriol diacetate benzoate Estriol glucuronide (Emmenin, Progynon) Estriol succinate Estriol tripropionate Estrone Estrone acetate Estrone sulfate Estropipate (piperazine estrone sulfate) Estrone tetraacetylglucoside Ethinyl estradiol^# Ethinyl estradiol sulfonate Hydroxyestrone diacetate Mestranol Methylestradiol Moxestrol Nilestriol Promestriene Quinestradol Quinestrol Non-steroidal: Benzestrol Bifluranol Chlorotrianisene Dienestrol Dienestrol diacetate Diethylstilbestrol (stilbestrol) Diethylstilbestrol diacetate Diethylstilbestrol dilaurate Diethylstilbestrol dipalmitate (stilpalmitate) Diethylstilbestrol dipropionate Diethylstilbestrol disulfate Diethylstilbestrol monobenzyl ether Dimestrol (diethylstilbestrol dimethyl ether) Fosfestrol (diethylstilbestrol diphosphate) Mestilbol (diethylstilbestrol monomethyl ether) Doisynoestrol (fenocycline) Hexestrol Hexestrol diacetate Hexestrol dicaprylate Hexestrol diphosphate Hexestrol dipropionate Methallenestril Methestrol dipropionate (promethestrol dipropionate) Paroxypropione Quadrosilan Zeranol

Progonadotropins	Antiandrogens (e.g., bicalutamide) GnRH agonists (e.g., GnRH (gonadorelin), leuprorelin) Gonadotropins (e.g., FSH, LH)

Antiestrogens

ER antagonists (incl. SERMs/SERDs)	Acolbifene^† Anordrin Bazedoxifene (+conjugated equine estrogens) Broparestrol Clomifene^# Cyclofenil Enclomifene^† Epitiostanol Etacstil ^§ Lasofoxifene Mepitiostane Ormeloxifene Ospemifene Raloxifene Tamoxifen^# Toremifene Exclusively antagonistic: Fulvestrant

Aromatase inhibitors	Non-selective: Aminoglutethimide Testolactone Selective: Anastrozole Exemestane Fadrozole Formestane Letrozole

Antigonadotropins	Androgens/anabolic steroids (e.g., testosterone, testosterone esters, nandrolone, oxandrolone, fluoxymesterone) D₂ receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride) GnRH agonists (e.g., leuprorelin, goserelin) GnRH antagonists (e.g., cetrorelix) Progestogens (e.g., chlormadinone acetate, cyproterone acetate, gestonorone caproate, hydroxyprogesterone caproate, medroxyprogesterone acetate, megestrol acetate)

Others	Mixed mechanism of action: Danazol Gestrinone

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

See also: Androgens and antiandrogens • Progestogens and antiprogestogens • Glucocorticoids and antiglucocorticoids • Mineralocorticoids and antimineralocorticoids • Gonadotropins and GnRH

Gonadotropins and GnRH (G03G)

Gonadotropin
preparations

Gonadotropins	Follicle-stimulating hormone Human chorionic gonadotropin Luteinizing hormone Menotropin Urofollitropin

Progonadotropins	Sex steroid antagonists (via disinhibition of the HPG axis): Antiandrogens (e.g., flutamide, bicalutamide, enzalutamide) Antiestrogens/SERMs (e.g., tamoxifen, clomifene, enclomifene) Aromatase inhibitors (e.g., anastrozole) GnRH agonists (e.g., GnRH)

Antigonadotropins	Sex steroids (via negative feedback on the HPG axis): Androgens (incl. anabolic steroids, e.g., nandrolone, oxandrolone) D₂ receptor antagonists (prolactin releasers) (incl., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride) Estrogens (incl., bifluranol, estradiol, ethinyl estradiol, diethylstilbestrol, paroxypropione) Progestogens (incl., chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate) Others (mixed mechanisms of action): Danazol Gestrinone

GnRH inhibitors

Agonists	Buserelin (buserelin acetate) Deslorelin Fertirelin (fertirelin acetate) GnRH (gonadorelin) Goserelin (goserelin acetate) Histrelin Leuprorelin (leuprolide acetate) Nafarelin Triptorelin

Antagonists	Abarelix Cetrorelix Degarelix Elagolix^† Ganirelix Relugolix^§

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

See also: Androgens and antiandrogens • Estrogens and antiestrogens • Progestogens and antiprogestogens

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