1,1,2-Trichloroethane

1,1,2-Trichloroethane

Names
IUPAC name 1,1,2-Trichloroethane
Other names 1,1,2-TCA vinyl trichloride beta-trichloroethane
Identifiers
CAS Number	79-00-5 Y
3D model (Jmol)	Interactive image Interactive image
ChEBI	CHEBI:36018 Y
ChEMBL	ChEMBL43882 Y
ChemSpider	6326 Y
ECHA InfoCard	100.001.061
KEGG	C19536 Y
PubChem	6574
UNII	28E9ERN9WU Y
InChI InChI=1S/C2H3Cl3/c3-1-2(4)5/h2H,1H2 Y Key: UBOXGVDOUJQMTN-UHFFFAOYSA-N Y InChI=1/C2H3Cl3/c3-1-2(4)5/h2H,1H2 Key: UBOXGVDOUJQMTN-UHFFFAOYAA
SMILES ClCC(Cl)Cl C(C(Cl)Cl)Cl
Properties
Chemical formula	C2H3Cl3
Molar mass	133.40 g/mol
Appearance	colorless liquid[1]
Odor	sweet, chloroform-like[1]
Density	1.435 g/cm3
Melting point	−37 °C (−35 °F; 236 K)
Boiling point	110 to 115 °C (230 to 239 °F; 383 to 388 K)
Solubility in water	0.4% (20°C)[1]
Vapor pressure	19 mmHg (20°C)[1]
Hazards
NFPA 704	1 3
Explosive limits	6%-15.5%[1]
Lethal dose or concentration (LD, LC):
LCLo (lowest published)	13,100 mg/m3 (cat, 4.5 hr) 2000 ppm (rat, 4 hr)[2]
US health exposure limits (NIOSH):
PEL (Permissible)	TWA 10 ppm (45 mg/m3) [skin][1]
REL (Recommended)	Ca TWA 10 ppm (45 mg/m3) [skin][1]
IDLH (Immediate danger)	Ca [100 ppm][1]
Related compounds
Related compounds	1,1,1-Trichloroethane; Trichloroethylene
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

1,1,2-Trichloroethane, or 1,1,2-TCA, is an organochloride solvent with the molecular formula C₂H₃Cl₃. It is a colourless, sweet-smelling liquid that does not dissolve in water, but is soluble in most organic solvents. It is an isomer of 1,1,1-trichloroethane.

It is used as a solvent and as an intermediate in the synthesis of 1,1-dichloroethane.

1,1,2-TCA is a central nervous system depressant and inhalation of vapors may cause dizziness, drowsiness, headache, nausea, shortness of breath, unconsciousness, or cancer.

Toxicology

Trichloroethane may be harmful by inhalation, ingestion and skin contact. It is a respiratory and eye irritant. Although no definitive studies currently exist, trichloroethane should be treated as a potential carcinogen since laboratory evidence suggests that low molecular weight chlorinated hydrocarbons may be carcinogenic.^[3]

The Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits to 1,1,2-Trichloroethane at 10 ppm over an eight-hour time-weighted average.^[4] It is considered to be a potential occupational carcinogen.

References