WDR45L
| WDR45B | |||||||||||||||||
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| Identifiers | |||||||||||||||||
| Aliases | WDR45B, WDR45L, WIPI-3, WIPI3, WD repeat domain 45B | ||||||||||||||||
| External IDs | MGI: 1914090 HomoloGene: 6028 GeneCards: WDR45B | ||||||||||||||||
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| Orthologs | |||||||||||||||||
| Species | Human | Mouse | |||||||||||||||
| Entrez | |||||||||||||||||
| Ensembl | |||||||||||||||||
| UniProt | |||||||||||||||||
| RefSeq (mRNA) | |||||||||||||||||
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| Location (UCSC) | Chr 17: 82.61 – 82.65 Mb | Chr 11: 121.33 – 121.35 Mb | |||||||||||||||
| PubMed search | [1] | [2] | |||||||||||||||
| Wikidata | |||||||||||||||||
| View/Edit Human | View/Edit Mouse |
WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3), also known as WD repeat-containing protein 45-like is a protein that in humans is encoded by the gene.[3]
Structure and function
WIPI-3 is a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein–protein interactions, and a conserved motif for interaction with phospholipids.[3]
See also
References
Further reading
- Brandenberger R, Wei H, Zhang S, et al. (2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
- Jeffries TR, Dove SK, Michell RH, Parker PJ (2004). "PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49.". Mol. Biol. Cell. 15 (6): 2652–63. doi:10.1091/mbc.E03-10-0732. PMC 420090
. PMID 15020712. - Proikas-Cezanne T, Waddell S, Gaugel A, et al. (2004). "WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy.". Oncogene. 23 (58): 9314–25. doi:10.1038/sj.onc.1208331. PMID 15602573.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.