Valerena-4,7(11)-diene synthase

Valerena-4,7(11)-diene synthase
Identifiers
EC number 4.2.3.139
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Valerena-4,7(11)-diene synthase (EC 4.2.3.139, VoTPS2) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, valerena-4,7(11)-diene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate valerena-4,7(11)-diene + diphosphate

This enzyme is isolated from the plant Valeriana officinalis (valerian).

References

  1. Pyle, B.W.; Tran, H.T.; Pickel, B.; Haslam, T.M.; Gao, Z.; Macnevin, G.; Vederas, J.C.; Kim, S.U.; Ro, D.K. (2012). "Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis)". FEBS J. 279: 3136–3146. doi:10.1111/j.1742-4658.2012.08692.x. PMID 22776156.
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