Upinder Singh Bhalla

Upinder Singh Bhalla (born 1963) is an Indian computational neuroscientist, academic and a professor at National Centre for Biological Sciences of the Tata Institute of Fundamental Research.^[1] He is known for his studies on neuronal and synaptic signaling in memory and olfactory coding using computational and experimental methods^[2] and is an elected fellow of the Indian Academy of Sciences^[3] and the Indian National Science Academy.^[4] The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2007, for his contributions to biological sciences.^[5]

Biography

Upinder S. Bhalla, born in the Indian capital of Delhi to an academic couple who were professors at Jawaharlal Nehru University, enrolled himself at the Indian Institute of Technology, Kanpur for an integrated master's program but discontinued his studies at IITL after one year to join Cambridge University from where he graduated in natural sciences.^[1] Subsequently, he secured a PhD under the guidance of James M. Bower from California Institute of Technology in 1993 and did his post doctoral studies at the laboratory of Ravi Iyengar at Mount Sinai School of Medicine.^[6] Returning to India, he joined National Centre for Biological Sciences, a Bengaluru-based biological research centre of Tata Institute of Fundamental Research where he became an assistant professor in 2002 and an associate professor in 2003, before becoming a professor in 2012.^[7] He heads a laboratory at NCBS where he hosts a number of research associates, post-doctoral fellows and doctoral students who are involved in the research on Memory and Plasticity through computational and experimental methods.^[8]

Legacy

Bhalla's researches are known to have widened our understanding of the memory functioning and he is credited with contributions in coding the olfactory information.^[9] His team at NCBS uses optogenetic techniques for monitoring brain cell activity and uses light to stimulate the activity.^[10] For their studies, Bhalla and his colleagues developed MOOSE (Multiscale Object-Oriented Simulation Environment), a simulation tool which helps build computer models of molecules and molecular networks.^[11] He has also developed olfactometers which measures the intensity of the sense of smell.^[12] His research findings have been published in a number of peer-reviewed articles^{[note 1]}; the online article repositories which have listed his articles include ResearchGate,^[13] PubMed^[14] and Academic Tree.^[15] He has mentored several research scholars in their doctoral and post-doctoral studies^[6][16] and is a member of the council of the Indian National Science Academy.^[17]

Awards and honors

Bhalla received the Shanti Swarup Bhatnagar Prize of the Council of Scientific and Industrial Research in 2007 for his contributions to Biological Sciences.^[5] The same year, the Indian Academy of Sciences elected him as their fellow.^[3] Three years later, he also became an elected fellow of the Indian National Science Academy.^[4]

Selected bibliography

• Upinder Singh Bhalla (July 2011). "Trafficking Motifs as the Basis for Two-Compartment Signaling Systems to Form Multiple Stable States". Biophys J. 101 (1): 21–32. doi:10.1016/j.bpj.2011.05.037. 
• Bhattacharyya U, Bhalla US (December 2015). "Robust and Rapid Air-Borne Odor Tracking without Casting". eNeuro. 2 (6). doi:10.1523/ENEURO.0102-15.2015. 
• Ray S, Chintaluri C, Bhalla US, Wójcik DK (April 2016). "NSDF: Neuroscience Simulation Data Format". Neuroinformatics. 14 (2): 147–67. doi:10.1007/s12021-015-9282-5.  CS1 maint: Multiple names: authors list (link)
• Gilra A, Bhalla US (May 2015). "Bulbar microcircuit model predicts connectivity and roles of interneurons in odor coding". PLoS One. 10 (5). doi:10.1371/journal.pone.0098045. 
• Gupta P, Albeanu DF, Bhalla US (February 2015). "Olfactory bulb coding of odors, mixtures and sniffs is a linear sum of odor time profiles". Nat Neurosci. 18 (2): 272–81. doi:10.1038/nn.3913.  CS1 maint: Multiple names: authors list (link)
• Jain P, Bhalla US (May 2014). "Transcription control pathways decode patterned synaptic inputs into diverse mRNA expression profiles". PLoS One. 9 (5). doi:10.1371/journal.pone.0095154. 
• Bhalla US (April 2014). "Molecular computation in neurons: a modeling perspective". Curr Opin Neurobiol. 25: 31–7. PMID 24709598. 
• Modi MN, Dhawale AK, Bhalla US (March 2014). "CA1 cell activity sequences emerge after reorganization of network correlation structure during associative learning". Elife. 3. doi:10.7554/eLife.01982.  CS1 maint: Multiple names: authors list (link)
• Bhalla US (2014). "Multiscale modeling and synaptic plasticity". Prog Mol Biol Transl Sci. 123: 351–86. doi:10.1016/B978-0-12-397897-4.00012-7. 

See also

• James M. Bower
• Ravi Iyengar

Notes

References

External links

• "Upinder Bhalla presents Multiscale Object Oriented Simulation Environment (MOOSE)". Computer demo at INCF Congress 2012, Munich, Germany. INCF Congress of Neuroinformatics. September 17, 2012. Retrieved October 25, 2016. 
• "Upinder S Bhalla on Labome". Validated Antibody Database. Labome. 2016. Retrieved October 25, 2016. 
• "Browse by Fellow". Articles of Upinder S Bhalla. Indian Academy of Sciences. 2016. Retrieved October 25, 2016.