Tetrahydropapaveroline
Names | |
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IUPAC name
1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol | |
Other names
Norlaudanosoline; Tetrahydroxypapaveroline | |
Identifiers | |
3D model (Jmol) | Interactive image |
PubChem | 18519 |
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Properties | |
C16H17NO4 | |
Molar mass | 287.32 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Tetrahydropapaveroline (norlaudanosoline) is a benzyltetrahydroisoquinoline alkaloid.[1]
It can be formed in trace amounts in the brain by a condensation reaction of dopamine and dopaldehyde (a metabolite of dopamine).[1][2]
It inhibits dopamine uptake within the cerebral cortex.
References
- 1 2 Richter, Derek. Addiction and Brain Damage. Routledge. p. 24. ISBN 9781315454030.
- ↑ RD Myers, CL Melchior (29 Apr 1977). "Alcohol drinking: abnormal intake caused by tetrahydropapaveroline in brain". Science. 196 (4289): 554–556. doi:10.1126/science.557839.
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