TMEM219

TMEM219
Identifiers
Aliases TMEM219, IGFBP-3R, transmembrane protein 219
External IDs MGI: 1915992 HomoloGene: 19263 GeneCards: TMEM219
Orthologs
Species Human Mouse
Entrez

124446

68742

Ensembl

ENSG00000149932

ENSMUSG00000060538

UniProt

Q86XT9

Q9D123

RefSeq (mRNA)

NM_001083613
NM_194280

NM_026827
NM_028389

RefSeq (protein)

NP_001077082.1
NP_919256.1

NP_081103.1
NP_082665.1

Location (UCSC) Chr 16: 29.94 – 29.97 Mb Chr 7: 126.89 – 126.92 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Transmembrane protein 219 also known as insulin-like growth factor-binding protein 3 receptor or IGFBP-3R is a protein that in humans is encoded by the TMEM219 gene.[3] IGFBP-3R acts as a cell death receptor for IGFBP3.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. "Entrez Gene: Transmembrane protein 219".
  4. Ingermann AR, Yang YF, Han J, Mikami A, Garza AE, Mohanraj L, Fan L, Idowu M, Ware JL, Kim HS, Lee DY, Oh Y (September 2010). "Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer". J. Biol. Chem. 285 (39): 30233–46. doi:10.1074/jbc.M110.122226. PMC 2943278Freely accessible. PMID 20353938.


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