TIPIN
| TIPIN | ||||||
|---|---|---|---|---|---|---|
| Identifiers | ||||||
| Aliases | TIPIN | |||||
| External IDs | MGI: 1921571 HomoloGene: 32373 GeneCards: TIPIN | |||||
| RNA expression pattern | ||||||
 | ||||||
| More reference expression data | ||||||
| Orthologs | ||||||
| Species | Human | Mouse | ||||
| Entrez | ||||||
| Ensembl | ||||||
| UniProt | ||||||
| RefSeq (mRNA) | ||||||
| RefSeq (protein) | ||||||
| Location (UCSC) | Chr 15: 66.34 – 66.39 Mb | Chr 9: 64.28 – 64.3 Mb | ||||
| PubMed search | [1] | [2] | ||||
| Wikidata | ||||||
| View/Edit Human | View/Edit Mouse |
TIMELESS-interacting protein is a protein that in humans is encoded by the TIPIN gene.[3][4][5]
Interactions
TIPIN has been shown to interact with Replication protein A1.[6]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Gotter AL (Aug 2003). "Tipin, a novel timeless-interacting protein, is developmentally co-expressed with timeless and disrupts its self-association". Journal of Molecular Biology. 331 (1): 167–76. doi:10.1016/S0022-2836(03)00633-8. PMID 12875843.
- ↑ Yoshizawa-Sugata N, Masai H (Jan 2007). "Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint". The Journal of Biological Chemistry. 282 (4): 2729–40. doi:10.1074/jbc.M605596200. PMID 17102137.
- ↑ "Entrez Gene: TIPIN TIMELESS interacting protein".
- ↑ Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK (Apr 2007). "The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement". Molecular and Cellular Biology. 27 (8): 3131–42. doi:10.1128/MCB.02190-06. PMC 1899931
. PMID 17296725.
Further reading
- Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK (Apr 2007). "The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement". Molecular and Cellular Biology. 27 (8): 3131–42. doi:10.1128/MCB.02190-06. PMC 1899931. PMID 17296725.
- Gotter AL, Suppa C, Emanuel BS (Feb 2007). "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors". Journal of Molecular Biology. 366 (1): 36–52. doi:10.1016/j.jmb.2006.10.097. PMID 17141802.
- Chou DM, Elledge SJ (Nov 2006). "Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function". Proceedings of the National Academy of Sciences of the United States of America. 103 (48): 18143–7. doi:10.1073/pnas.0609251103. PMC 1654129. PMID 17116885.
- Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
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