Sulfur oxygenase/reductase

In enzymology, a sulfur oxygenase/reductase (EC 1.13.11.55) is an enzyme that catalyzes the chemical reaction

4 sulfur + 4 H₂O + O₂ 2 hydrogen sulfide + 2 bisulfite + 2 H⁺

The 3 substrates of this enzyme are sulfur, H₂O, and O₂, whereas its 3 products are hydrogen sulfide, bisulfite, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O₂. The systematic name of this enzyme class is sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming). Other names in common use include SOR, sulfur oxygenase, and sulfur oxygenase reductase.

References

• Kletzin A (1989). "Coupled enzymatic production of sulfite, thiosulfate, and hydrogen sulfide from sulfur: purification and properties of a sulfur oxygenase reductase from the facultatively anaerobic archaebacterium Desulfurolobus ambivalens". J. Bacteriol. 171 (3): 1638–43. PMC 209792. PMID 2493451. 
• Kletzin A (1992). "Molecular characterization of the sor gene, which encodes the sulfur oxygenase/reductase of the thermoacidophilic Archaeum Desulfurolobus ambivalens". J. Bacteriol. 174 (18): 5854–9. PMC 207119. PMID 1522063. 
• Sun CW, Chen ZW, He ZG, Zhou PJ, Liu SJ (2003). "Purification and properties of the sulfur oxygenase/reductase from the acidothermophilic archaeon, Acidianus strain S5". Extremophiles. 7 (2): 131–4. doi:10.1007/s00792-002-0304-5. PMID 12664265. 
• Scholz C, Teixeira M, Gomes CM, Kletzin A (2004). "The sulphur oxygenase reductase from Acidianus ambivalens is a multimeric protein containing a low-potential mononuclear non-haem iron centre". Biochem. J. 381 (Pt 1): 137–46. doi:10.1042/BJ20040003. PMC 1133771. PMID 15030315.