SGPL1

SGPL1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases SGPL1, S1PL, SPL, sphingosine-1-phosphate lyase 1
External IDs MGI: 1261415 HomoloGene: 2897 GeneCards: SGPL1
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

8879

20397

Ensembl

ENSG00000166224

ENSMUSG00000020097

UniProt

O95470

Q8R0X7

RefSeq (mRNA)

NM_003901

NM_009163
NM_001316673
NM_001316674

RefSeq (protein)

NP_003892.2

NP_001303602.1
NP_001303603.1
NP_033189.2

Location (UCSC) Chr 10: 70.82 – 70.88 Mb Chr 10: 61.1 – 61.15 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Sphingosine-1-phosphate lyase 1 is an enzyme that in humans is encoded by the SGPL1 gene.[3][4][5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Zhou J, Saba JD (Mar 1998). "Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast". Biochem Biophys Res Commun. 242 (3): 502–7. doi:10.1006/bbrc.1997.7993. PMID 9464245.
  4. Oskouian B, Sooriyakumaran P, Borowsky AD, Crans A, Dillard-Telm L, Tam YY, Bandhuvula P, Saba JD (Nov 2006). "Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer". Proc Natl Acad Sci U S A. 103 (46): 17384–9. doi:10.1073/pnas.0600050103. PMC 1859938Freely accessible. PMID 17090686.
  5. "Entrez Gene: SGPL1 sphingosine-1-phosphate lyase 1".

Further reading


This article is issued from Wikipedia - version of the 6/3/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.