Serous carcinoma
| Serous carcinoma | |
|---|---|
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| Micrograph of serous carcinoma. | |
| Classification and external resources |
In pathology, serous carcinoma is an epithelial malignancy (carcinoma) that arises from the lining of a cavity that produces a serum-like fluid (a serous cavity).
Serous lined cavities include the peritoneum, pericardium and pleural space and tunica vaginalis.[1]
Cytologic features
Cytologic features of serous carcinoma are:
- Marked intragroup nuclear pleomorphism.
- Macronucleoli.
- "Knobby" group borders (in large groups).
- Hydropic vacuoles.
Symptoms of serous carcinoma may include:[2]
- Discomfort/pain or bloating in abdomen
- Frequent urination
- Weight loss
Differential diagnosis
The differential diagnosis of serous carcinoma not otherwise specified includes:
- Ovarian serous carcinoma, a type of ovarian cancer.
- Uterine serous carcinoma, also known as uterine papillary serous carcinoma, a type of uterine cancer.
- Fallopian tube serous carcinoma, a type of uterine tube cancer.
- Cervical serous carcinoma, a rare type of cervical cancer.
- Primary peritoneal serous carcinoma, a very rare cancer that arise from the peritoneum.
There has been the suggestion that the above diagnoses really represent one entity.[3]
See also
References
- ↑ Serous Membranes & Cavities Lecture. Veterinary Anatomy Web Site. University of Minnesota. URL: http://vanat.cvm.umn.edu/TFFlectPDFs/LectSerousCavities.pdf. Accessed on: February 6, 2010.
- ↑ "Serous Carcinoma: A Detailed Guide". The CG Law Firm. Retrieved 26 October 2014.
- ↑ Dubeau, L. (Dec 2008). "The cell of origin of ovarian epithelial tumours.". Lancet Oncol. 9 (12): 1191–7. doi:10.1016/S1470-2045(08)70308-5. PMID 19038766.
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