SMC4

SMC4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases SMC4, CAP-C, CAPC, SMC-4, SMC4L1, hCAP-C, structural maintenance of chromosomes 4
External IDs MGI: 1917349 HomoloGene: 4015 GeneCards: SMC4
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

10051

70099

Ensembl

ENSG00000113810

ENSMUSG00000034349

UniProt

Q9NTJ3

Q8CG47

RefSeq (mRNA)

NM_001002799
NM_001002800
NM_001288753
NM_005496

NM_133786

RefSeq (protein)

NP_001002800.1
NP_001275682.1
NP_005487.3

NP_598547.1

Location (UCSC) Chr 3: 160.4 – 160.43 Mb Chr 3: 69 – 69.03 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Structural maintenance of chromosomes protein 4 (SMC-4) also known as chromosome-associated polypeptide C (CAP-C) or XCAP-C homolog is a protein that in humans is encoded by the SMC4 gene.[3][4][5] SMC-4 is a core subunit of condensin I and II, large protein complexes involved in chromosome condensation.

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Schmiesing JA, Ball AR Jr, Gregson HC, Alderton JM, Zhou S, Yokomori K (Nov 1998). "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics". Proc Natl Acad Sci U S A. 95 (22): 12906–11. doi:10.1073/pnas.95.22.12906. PMC 23650Freely accessible. PMID 9789013.
  4. Nishiwaki T, Daigo Y, Kawasoe T, Nagasawa Y, Ishiguro H, Fujita M, Furukawa Y, Nakamura Y (Jun 1999). "Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family". J Hum Genet. 44 (3): 197–202. doi:10.1007/s100380050142. PMID 10319587.
  5. "Entrez Gene: SMC4 structural maintenance of chromosomes 4".

Further reading


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