SEC22B

SEC22B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases SEC22B, ERS-24, SEC22L1, SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)
External IDs MGI: 1338759 HomoloGene: 3597 GeneCards: SEC22B
Orthologs
Species Human Mouse
Entrez

9554

20333

Ensembl

ENSG00000265808

ENSMUSG00000027879

UniProt

O75396

O08547

RefSeq (mRNA)

NM_004892

NM_011342

RefSeq (protein)

NP_004883.3

NP_035472.1

Location (UCSC) Chr 1: 120.15 – 120.18 Mb Chr 3: 97.9 – 97.92 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Vesicle-trafficking protein SEC22b is a protein that in humans is encoded by the SEC22B gene.[3][4][5]

The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript.[5] SEC22B has been shown to interact with syntaxin 18.

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Hay JC; Chao DS; Kuo CS; Scheller RH (Apr 1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells". Cell. 89 (1): 149–58. doi:10.1016/S0092-8674(00)80191-9. PMID 9094723.
  4. Okumura AJ; Hatsuzawa K; Tamura T; Nagaya H; Saeki K; Okumura F; Nagao K; Nishikawa M; Yoshimura A; Wada I (Feb 2006). "Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system". J Biol Chem. 281 (7): 4495–506. doi:10.1074/jbc.M509715200. PMID 16354670.
  5. 1 2 "Entrez Gene: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae)".

Further reading


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