RAB34

RAB34

Identifiers

RAB34, RAB39, RAH, member RAS oncogene family

External IDs

MGI: 104606 HomoloGene: 12908 GeneCards: RAB34

Gene ontology
Molecular function	• nucleotide binding • Ral GTPase binding • GTP binding • protein binding
Cellular component	• cytoplasm • vesicle • phagocytic vesicle membrane • Golgi apparatus • membrane • Golgi cisterna • ruffle membrane • phagocytic vesicle • perinuclear region of cytoplasm • Golgi stack • extracellular exosome • cytoplasmic vesicle • nucleus • nucleolus
Biological process	• antigen processing and presentation • phagosome-lysosome fusion • small GTPase mediated signal transduction • phagosome maturation • lysosome localization • macropinocytosis • transport • protein transport • protein localization to plasma membrane • Golgi to plasma membrane protein transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


83871


19376


ENSG00000109113


ENSMUSG00000002059


Q9BZG1 P0DI83


Q64008

RefSeq (mRNA)

NM_031934 NM_001142624 NM_001142625 NM_001144942 NM_001144943
NM_001256276 NM_001256277 NM_001256278


NM_001159482 NM_033475

RefSeq (protein)

NP_001138414.1 NP_001243205.1 NP_001243206.1 NP_001243207.1 NP_114140.4
NP_001243210.1


NP_001152954.1 NP_258436.2

Location (UCSC)

Chr 17: 28.71 – 28.72 Mb

Chr 11: 78.19 – 78.19 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Ras-related protein Rab-34 is a protein that in humans is encoded by the RAB34 gene.^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Sun P, Yamamoto H, Suetsugu S, Miki H, Takenawa T, Endo T (Feb 2003). "Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation". J Biol Chem. 278 (6): 4063–71. doi:10.1074/jbc.M208699200. PMID 12446704.
↑ "Entrez Gene: RAB34 RAB34, member RAS oncogene family".

Further reading

Wang T, Hong W (2003). "Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rab-interacting lysosomal protein.". Mol. Biol. Cell. 13 (12): 4317–32. doi:10.1091/mbc.E02-05-0280. PMC 138636. PMID 12475955.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Chen T, Han Y, Yang M, et al. (2003). "Rab39, a novel Golgi-associated Rab GTPase from human dendritic cells involved in cellular endocytosis.". Biochem. Biophys. Res. Commun. 303 (4): 1114–20. doi:10.1016/S0006-291X(03)00482-0. PMID 12684051.
Wang T, Wong KK, Hong W (2004). "A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34.". Mol. Biol. Cell. 15 (2): 815–26. doi:10.1091/mbc.E03-06-0413. PMC 329395. PMID 14668488.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
Colucci AM, Campana MC, Bellopede M, Bucci C (2005). "The Rab-interacting lysosomal protein, a Rab7 and Rab34 effector, is capable of self-interaction.". Biochem. Biophys. Res. Commun. 334 (1): 128–33. doi:10.1016/j.bbrc.2005.06.067. PMID 15996637.
Speight P, Silverman M (2005). "Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34.". Traffic. 6 (10): 858–65. doi:10.1111/j.1600-0854.2005.00321.x. PMID 16138900.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Coyne CB, Shen L, Turner JR, Bergelson JM (2007). "Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5.". Cell Host Microbe. 2 (3): 181–92. doi:10.1016/j.chom.2007.07.003. PMC 2719558. PMID 18005733.

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