Proton-dependent oligopeptide transporter
| POT family | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | PTR2 | ||||||||
| Pfam | PF00854 | ||||||||
| InterPro | IPR000109 | ||||||||
| PROSITE | PDOC00784 | ||||||||
| TCDB | 2.A.17 | ||||||||
| OPM superfamily | 15 | ||||||||
| OPM protein | 2xut | ||||||||
| |||||||||
The transport of peptides into cells is a well-documented biological phenomenon which is accomplished by specific, energy-dependent transporters found in a number of organisms as diverse as bacteria and humans. The proton-dependent oligopeptide transporter (PTR) family of proteins is distinct from the ABC-type peptide transporters and was uncovered by sequence analyses of a number of recently discovered peptide transport proteins.[1] These proteins that seem to be mainly involved in the intake of small peptides with the concomitant uptake of a proton.[2]
Subfamilies
- Oligopeptide transporter, peptide:H+ symporter InterPro: IPR004768
- Amino acid/peptide transporter InterPro: IPR005279
Human proteins containing this domain
FP12591; PEPT1; PTR4; SLC15A1; SLC15A2; SLC15A3; SLC15A4; hPEPT1-RF;
References
- ↑ Naider F, Becker JM, Steiner HY (1995). "The PTR family: a new group of peptide transporters". Mol. Microbiol. 16 (5): 825–834. doi:10.1111/j.1365-2958.1995.tb02310.x. PMID 7476181.
- ↑ Skurray RA, Paulsen IT (1994). "The POT family of transport proteins". Trends Biochem. Sci. 19 (10): 404–404. doi:10.1016/0968-0004(94)90087-6. PMID 7817396.
This article incorporates text from the public domain Pfam and InterPro IPR000109
This article is issued from Wikipedia - version of the 12/5/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.