PIGB

PIGB
Identifiers
Aliases PIGB, GPI-MT-III, PIG-B, phosphatidylinositol glycan anchor biosynthesis class B
External IDs MGI: 1891825 HomoloGene: 3570 GeneCards: PIGB
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

9488

55981

Ensembl

ENSG00000069943

ENSMUSG00000079469

UniProt

Q92521

Q9JJQ0

RefSeq (mRNA)

NM_004855

NM_018889

RefSeq (protein)

NP_004846.4

NP_061377.2

Location (UCSC) Chr 15: 55.32 – 55.36 Mb Chr 9: 73.01 – 73.04 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

GPI mannosyltransferase 3 is an enzyme that in humans is encoded by the PIGB gene.[3][4]

This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases.[4]

References

Further reading


This article is issued from Wikipedia - version of the 6/3/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.