Osteoradionecrosis

MRI showing osteoradionecrosis in the cervical vertebrae following radiotherapy for laryngeal cancer.

Osteoradionecrosis is a possible complication following radiotherapy where an area of bone does not heal from irradiation. Irradiation of bones causes damage to osteocytes and impairs the blood supply. The affected hard tissues become hypovascular (reduced number of blood vessels), hypocellular (reduced number of cells) and hypoxic (low levels of oxygen). Osteoradionecrosis usually occurs in the mandible, and causes chronic pain and surface ulceration. Prevention of osteradionecrosis is part of the reason all teeth of questionable prognosis are removed before the start of a course of radiotherapy.^[1]

References

↑ Bouquot, Brad W. Neville , Douglas D. Damm, Carl M. Allen, Jerry E. (2002). Oral & maxillofacial pathology (2. ed.). Philadelphia: W.B. Saunders. p. 263. ISBN 0-7216-9003-3.

Oral and maxillofacial pathology (K00–K06, K11–K14, 520–525, 527–529)

Lips

Cheilitis Actinic Angular Plasma cell Cleft lip Congenital lip pit Eclabium Herpes labialis Macrocheilia Microcheilia Nasolabial cyst Sun poisoning Trumpeter's wart

Tongue

Ankyloglossia Black hairy tongue Caviar tongue Crenated tongue Cunnilingus tongue Fissured tongue Foliate papillitis Glossitis Geographic tongue Median rhomboid glossitis Transient lingual papillitis Glossoptosis Hypoglossia Lingual thyroid Macroglossia Microglossia Rhabdomyoma

Palate

Bednar's aphthae Cleft palate High-arched palate Palatal cysts of the newborn Inflammatory papillary hyperplasia Stomatitis nicotina Torus palatinus

Oral mucosa - Lining of mouth

Teeth (pulp, dentin, enamel)

Periodontium (gingiva, periodontal ligament, cementum, alveolus) - Gums and tooth-supporting structures

Periapaical, mandibular and maxillary hard tissues - Bones of jaws

Temporomandibular joints, muscles of mastication and malocclusions - Jaw joints, chewing muscles and bite abnormalities

Bruxism Condylar resorption Mandibular dislocation Malocclusion Crossbite Open bite Overbite Overjet Prognathia Retrognathia Temporomandibular joint dysfunction

Salivary glands

Orofacial soft tissues - Soft tissues around the mouth

Actinomycosis Angioedema Basal cell carcinoma Cutaneous sinus of dental origin Cystic hygroma Gnathophyma Ludwig's angina Macrostomia Melkersson–Rosenthal syndrome Microstomia Noma Oral Crohn's disease Orofacial granulomatosis Perioral dermatitis Pyostomatitis vegetans

Other

Eagle syndrome Hemifacial hypertrophy Facial hemiatrophy Oral manifestations of systemic disease

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