Nitric oxide reductase (NAD(P), nitrous oxide-forming)
| Nitric oxide reductase (NAD(P), nitrous oxide-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.7.1.14 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Nitric oxide reductase (NAD(P), nitrous oxide-forming) (EC 1.7.1.14, fungal nitric oxide reductase, cytochrome P450nor, NOR (ambiguous)) is an enzyme with systematic name nitrous oxide:NAD(P) oxidoreductase.[1][2][3][4] This enzyme catalyses the following chemical reaction
- N2O + NAD(P)+ + H2O 2 NO + NAD(P)H + H+
This enzyme is heme-thiolate protein (P450).
References
- ↑ Shoun, H.; Tanimoto, T. (1991). "Denitrification by the fungus Fusarium oxysporum and involvement of cytochrome P-450 in the respiratory nitrite reduction". J. Biol. Chem. 266 (17): 11078–11082. PMID 2040619.
- ↑ Shiro, Y.; Fujii, M.; Iizuka, T.; Adachi, S.; Tsukamoto, K.; Nakahara, K.; Shoun, H. (1995). "Spectroscopic and kinetic studies on reaction of cytochrome P450nor with nitric oxide. Implication for its nitric oxide reduction mechanism". J. Biol. Chem. 270 (4): 1617–1623. PMID 7829493.
- ↑ Zhang, L.; Kudo, T.; Takaya, N.; Shoun, H. (2002). "The B′ helix determines cytochrome P450nor specificity for the electron donors NADH and NADPH". J. Biol. Chem. 277: 33842–33847. doi:10.1074/jbc.M203923200. PMID 12105197.
- ↑ Oshima, R.; Fushinobu, S.; Su, F.; Zhang, L.; Takaya, N.; Shoun, H. (2004). "Structural evidence for direct hydride transfer from NADH to cytochrome P450nor". J. Mol. Biol. 342: 207–217. doi:10.1016/j.jmb.2004.07.009. PMID 15313618.
External links
- Nitric oxide reductase (NAD(P), nitrous oxide-forming) at the US National Library of Medicine Medical Subject Headings (MeSH)
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