Nitrate reductase (quinone)
| Nitrate reductase (quinone) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.7.5.1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Nitrate reductase (quinone) (EC 1.7.5.1, nitrate reductase A, nitrate reductase Z, quinol/nitrate oxidoreductase, quinol-nitrate oxidoreductase, quinol:nitrate oxidoreductase, NarA, NarZ, NarGHI) is an enzyme with systematic name nitrite:quinone oxidoreductase.[1][2][3][4][5][6][7] This enzyme catalyses the following chemical reaction
This is a membrane-bound enzyme which supports [anaerobic respiration] on nitrate.
References
- ↑ Enoch, H.G.; Lester, R.L. (1974). "The role of a novel cytochrome b-containing nitrate reductase and quinone in the in vitro reconstruction of formate-nitrate reductase activity of E. coli". Biochem. Biophys. Res. Commun. 61 (4): 1234–1241. doi:10.1016/s0006-291x(74)80416-x. PMID 4616697.
- ↑ Bertero, M.G.; Rothery, R.A.; Palak, M.; Hou, C.; Lim, D.; Blasco, F.; Weiner, J.H.; Strynadka, N.C. (2003). "Insights into the respiratory electron transfer pathway from the structure of nitrate reductase A". Nat. Struct. Biol. 10: 681–687. doi:10.1038/nsb969. PMID 12910261.
- ↑ Lanciano, P.; Magalon, A.; Bertrand, P.; Guigliarelli, B.; Grimaldi, S. (2007). "High-stability semiquinone intermediate in nitrate reductase A (NarGHI) from Escherichia coli is located in a quinol oxidation site close to heme bD". Biochemistry. 46 (18): 5323–5329. doi:10.1021/bi700074y. PMID 17439244.
- ↑ Bertero, M.G.; Rothery, R.A.; Boroumand, N.; Palak, M.; Blasco, F.; Ginet, N.; Weiner, J.H.; Strynadka, N.C. (2005). "Structural and biochemical characterization of a quinol binding site of Escherichia coli nitrate reductase A". J. Biol. Chem. 280 (15): 14836–14843. doi:10.1074/jbc.M410457200. PMID 15615728.
- ↑ Bonnefoy, V.; Demoss, J.A. (1994). "Nitrate reductases in Escherichia coli". Antonie Van Leeuwenhoek. 66 (1-3): 47–56. doi:10.1007/bf00871632. PMID 7747940.
- ↑ Guigliarelli, B.; Asso, M.; More, C.; Augier, V.; Blasco, F.; Pommier, J.; Giordano, G.; Bertrand, P. (1992). "EPR and redox characterization of iron-sulfur centers in nitrate reductases A and Z from Escherichia coli. Evidence for a high-potential and a low-potential class and their relevance in the electron-transfer mechanism". Eur. J. Biochem. 207 (1): 61–68. doi:10.1111/j.1432-1033.1992.tb17020.x. PMID 1321049.
- ↑ Iobbi-Nivol, C.; Santini, C.L.; Blasco, F.; Giordano, G. (1990). "Purification and further characterization of the second nitrate reductase of Escherichia coli K12". Eur. J. Biochem. 188 (3): 679–687. doi:10.1111/j.1432-1033.1990.tb15450.x. PMID 2139607.
External links
- Nitrate reductase (quinone) at the US National Library of Medicine Medical Subject Headings (MeSH)
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