Neochromosome

A neochromosome is a chromosome that is not normally found in nature. Cancer-associated neochromosomes are found in some cancer cells.[1][2]

Neochromosomes have also been created using genetic engineering techniques.[3][4]

References

  1. ↑ Garsed, D. W.; Marshall, O. J.; Corbin, V. D. A.; Hsu, A.; Di Stefano, L.; Schröder, J.; Li, J.; Feng, Z. P.; Kim, B. W.; Kowarsky, M.; Lansdell, B.; Brookwell, R.; Myklebost, O.; Meza-Zepeda, L.; Holloway, A. J.; Pedeutour, F.; Choo, K. H. A.; Damore, M. A.; Deans, A. J.; Papenfuss, A. T.; Thomas, D. M. (2014). "The Architecture and Evolution of Cancer Neochromosomes". Cancer Cell. 26 (5): 653. doi:10.1016/j.ccell.2014.09.010.
  2. ↑ Garsed, D. W.; Holloway, A. J.; Thomas, D. M. (2009). "Cancer-associated neochromosomes: A novel mechanism of oncogenesis". BioEssays. 31 (11): 1191–200. doi:10.1002/bies.200800208. PMID 19795405.
  3. ↑ Callaway, E. (2014). "First synthetic yeast chromosome revealed". Nature. doi:10.1038/nature.2014.14941.
  4. ↑ Alan Boyle (27 March 2014). "Gene Gurus Create Synthetic Yeast Chromosome From Scratch". NBC News.


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