Methylphosphonate synthase

Methylphosphonate synthase
Identifiers
EC number 1.13.11.73
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Methylphosphonate synthase (EC 1.13.11.73, mpnS (gene)) is an enzyme with systematic name 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (methylphosphonate forming).[1] This enzyme catalyses the following chemical reaction

2-hydroxyethylphosphonate + O2 methylphosphonate + HCO3−

Methylphosphonate synthase is isolated from the marine archaeon Nitrosopumilus maritimus.

References

  1. Metcalf, W.W.; Griffin, B.M.; Cicchillo, R.M.; Gao, J.; Janga, S.C.; Cooke, H.A.; Circello, B.T.; Evans, B.S.; Martens-Habbena, W.; Stahl, D.A.; van der Donk, W.A. (2012). "Synthesis of methylphosphonic acid by marine microbes: a source for methane in the aerobic ocean". Science. 337 (6098): 1104–1107. doi:10.1126/science.1219875. PMC 3466329Freely accessible. PMID 22936780.
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