KIFC3

KIFC3

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2H58

Identifiers

External IDs

MGI: 109202 HomoloGene: 124421 GeneCards: KIFC3

Gene ontology
Molecular function	• microtubule motor activity • nucleotide binding • microtubule binding • ATP-dependent microtubule motor activity, minus-end-directed • ATPase activity • protein binding • ATP binding
Cellular component	• cytoplasm • centrosome • Golgi apparatus • membrane • kinesin complex • adherens junction • microtubule organizing center • cell junction • zonula adherens • microtubule • extracellular exosome • cytoplasmic vesicle membrane • cytoskeleton • cytoplasmic vesicle
Biological process	• Golgi organization • epithelial cell-cell adhesion • microtubule-based movement • zonula adherens maintenance • microtubule-based process • visual perception
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


3801


16582


ENSG00000140859


ENSMUSG00000031788


Q9BVG8


O35231

RefSeq (mRNA)

NM_001130099 NM_001130100 NM_005550 NM_001318710 NM_001318711
NM_001318712 NM_001318713 NM_001318714 NM_001318715


NM_001145831 NM_001145832 NM_010631

RefSeq (protein)

NP_001123571.1 NP_001123572.1 NP_005541.3 NP_001305639.1 NP_001305640.1
NP_001305641.1 NP_001305642.1 NP_001305643.1 NP_001305644.1


NP_001139303.1 NP_001139304.1 NP_034761.3

Location (UCSC)

Chr 16: 57.76 – 57.86 Mb

Chr 8: 95.1 – 95.14 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Kinesin-like protein KIFC3 is a protein that in humans is encoded by the KIFC3 gene.^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Hoang EH, Whitehead JL, Dose AC, Burnside B (Dec 1998). "Cloning of a novel C-terminal kinesin (KIFC3) that maps to human chromosome 16q13-q21 and thus is a candidate gene for Bardet-Biedl syndrome". Genomics. 52 (2): 219–22. doi:10.1006/geno.1998.5431. PMID 9782090.
↑ "Entrez Gene: KIFC3 kinesin family member C3".

Further reading

Diu A, Moebius U, Ferradini L, et al. (1993). "Limited T-cell receptor diversity in liver-infiltrating lymphocytes from patients with primary biliary cirrhosis.". J. Autoimmun. 6 (5): 611–9. doi:10.1006/jaut.1993.1050. PMID 8240664.
Hoang E, Bost-Usinger L, Burnside B (1999). "Characterization of a novel C-kinesin (KIFC3) abundantly expressed in vertebrate retina and RPE.". Exp. Eye Res. 69 (1): 57–68. doi:10.1006/exer.1999.0671. PMID 10375449.
Noda Y, Okada Y, Saito N, et al. (2001). "KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated Triton-insoluble membranes.". J. Cell Biol. 155 (1): 77–88. doi:10.1083/jcb.200108042. PMC 2150803. PMID 11581287.
Xu Y, Takeda S, Nakata T, et al. (2002). "Role of KIFC3 motor protein in Golgi positioning and integration.". J. Cell Biol. 158 (2): 293–303. doi:10.1083/jcb.200202058. PMC 2173137. PMID 12135985.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Roni V, Carpio R, Wissinger B (2007). "Mapping of transcription start sites of human retina expressed genes.". BMC Genomics. 8: 42. doi:10.1186/1471-2164-8-42. PMC 1802077. PMID 17286855.

PDB gallery

2h58: Crystal structure of the KIFC3 motor domain in complex with ADP

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