KIFC1

KIFC1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2REP
Identifiers
Aliases	KIFC1, HSET, KNSL2, kinesin family member C1
External IDs	MGI: 2137414 HomoloGene: 83229 GeneCards: KIFC1
Gene ontology Molecular function • nucleotide binding • microtubule binding • ATPase activity • ATP binding • microtubule motor activity Cellular component • cytoplasm • endosome • membrane • kinesin complex • spindle • microtubule organizing center • early endosome • microtubule • cytoskeleton • nucleus Biological process • mitotic nuclear division • cell division • mitotic spindle assembly • spermatogenesis • mitotic sister chromatid segregation • cell cycle • mitotic metaphase plate congression • microtubule-based movement Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3833	16580
Ensembl	n/a	ENSMUSG00000024301
UniProt	Q9BW19	Q9QWT9
RefSeq (mRNA)	NM_002263	NM_016761 NM_053173
RefSeq (protein)	NP_002254.2	NP_001182227.1 NP_444403.2
Location (UCSC)	Chr 6: 33.39 – 33.41 Mb	Chr 17: 26.92 – 26.93 Mb
PubMed search	[1]	[2]
Wikidata

Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.^[3][4]

Function

The protein KifC1 is a member of kinesin-14 family. KifC1 consists of C-terminal motor domain, superhelical stalk and N-terminal tail domain. Tail and motor domains contain microtubule-binding sites. This kinesin moves towards the minus-end of microtubule and has an ability to slide or crosslink microtubules. KifC1 functions during mitotic spindle formation.

References

Further reading