ISG20

ISG20
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases ISG20, CD25, HEM45, interferon stimulated exonuclease gene 20kDa, interferon stimulated exonuclease gene 20
External IDs MGI: 1928895 HomoloGene: 31081 GeneCards: ISG20
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

3669

57444

Ensembl

ENSG00000172183

ENSMUSG00000039236

UniProt

Q96AZ6

Q9JL16

RefSeq (mRNA)

NM_001113527
NM_001291220
NM_001291221
NM_020583

RefSeq (protein)

NP_001290162.1
NP_001290163.1
NP_001290165.1
NP_002192.2

NP_001106999.1
NP_001278149.1
NP_001278150.1
NP_065608.2

Location (UCSC) Chr 15: 88.64 – 88.66 Mb Chr 7: 78.91 – 78.92 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Interferon-stimulated gene 20 kDa protein is a protein that in humans is encoded by the ISG20 gene.[3][4][5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Gongora C, David G, Pintard L, Tissot C, Hua TD, Dejean A, Mechti N (Aug 1997). "Molecular cloning of a new interferon-induced PML nuclear body-associated protein". The Journal of Biological Chemistry. 272 (31): 19457–63. doi:10.1074/jbc.272.31.19457. PMID 9235947.
  4. Mattei MG, Tissot C, Gongora C, Mechti N (Jun 1998). "Assignment of ISG20 encoding a new interferon-induced PML nuclear body-associated protein, to chromosome 15q26 by in situ hybridization". Cytogenetics and Cell Genetics. 79 (3-4): 286–7. doi:10.1159/000134745. PMID 9605874.
  5. "Entrez Gene: ISG20 interferon stimulated exonuclease gene 20kDa".

Further reading

  • Pentecost BT (Jan 1998). "Expression and estrogen regulation of the HEM45 MRNA in human tumor lines and in the rat uterus". The Journal of Steroid Biochemistry and Molecular Biology. 64 (1-2): 25–33. doi:10.1016/S0960-0760(97)00140-4. PMID 9569007. 
  • Nguyen LH, Espert L, Mechti N, Wilson DM (Jun 2001). "The human interferon- and estrogen-regulated ISG20/HEM45 gene product degrades single-stranded RNA and DNA in vitro". Biochemistry. 40 (24): 7174–9. doi:10.1021/bi010141t. PMID 11401564. 
  • Izmailova E, Bertley FM, Huang Q, Makori N, Miller CJ, Young RA, Aldovini A (Feb 2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages". Nature Medicine. 9 (2): 191–7. doi:10.1038/nm822. PMID 12539042. 
  • Espert L, Degols G, Gongora C, Blondel D, Williams BR, Silverman RH, Mechti N (May 2003). "ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses". The Journal of Biological Chemistry. 278 (18): 16151–8. doi:10.1074/jbc.M209628200. PMID 12594219. 
  • Horio T, Murai M, Inoue T, Hamasaki T, Tanaka T, Ohgi T (Nov 2004). "Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease". FEBS Letters. 577 (1-2): 111–6. doi:10.1016/j.febslet.2004.09.074. PMID 15527770. 


This article is issued from Wikipedia - version of the 5/20/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.