Hydroxylamine dehydrogenase
Hydroxylamine dehydrogenase | |||||||||
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Identifiers | |||||||||
EC number | 1.7.2.6 | ||||||||
CAS number | 9075-43-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Hydroxylamine dehydrogenase (EC 1.7.2.6, HAO (ambiguous)) is an enzyme with systematic name hydroxylamine:ferricytochrome-c oxidoreductase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- (1) hydroxylamine + H2O + 2 ferricytochrome c nitrite + 2 ferrocytochrome c + 5 H+
- (2) hydroxylamine + ferricytochrome c nitric oxide + ferrocytochrome c + 3 H+
The enzymes from the nitrifying bacterium Nitrosomonas europaea and the methylotrophic bacterium Methylococcus capsulatus are hemoproteins.
References
- ↑ Rees, M. (1968). "Studies of the hydroxylamine metabolism of Nitrosomonas europaea. I. Purification of hydroxylamine oxidase". Biochemistry. 7: 353–366. doi:10.1021/bi00841a045. PMID 5758552.
- ↑ Hooper, A.B.; Terry, K.R. (1979). "Hydroxylamine oxidoreductase of Nitrosomonas. Production of nitric oxide from hydroxylamine". Biochim. Biophys. Acta. 571 (1): 12–20. doi:10.1016/0005-2744(79)90220-1. PMID 497235.
- ↑ Hooper, A.B.; Balny, C. (1982). "Reaction of oxygen with hydroxylamine oxidoreductase of Nitrosomonas: fast kinetics". FEBS Lett. 144: 299–303. doi:10.1016/0014-5793(82)80658-3. PMID 7117545.
- ↑ Lipscomb, J.D.; Hooper, A.B. (1982). "Resolution of multiple heme centers of hydroxylamine oxidoreductase from Nitrosomonas. 1. Electron paramagnetic resonance spectroscopy". Biochemistry. 21: 3965–3972. doi:10.1021/bi00260a010. PMID 6289867.
- ↑ Poret-Peterson, A.T.; Graham, J.E.; Gulledge, J.; Klotz, M.G. (2008). "Transcription of nitrification genes by the methane-oxidizing bacterium, Methylococcus capsulatus strain Bath". ISME J. 2 (12): 1213–1220. doi:10.1038/ismej.2008.71. PMID 18650926.
External links
- Hydroxylamine dehydrogenase at the US National Library of Medicine Medical Subject Headings (MeSH)
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