Gerard Kleywegt

Gerard Kleywegt
Born Gerrit Jacob Kleijwegt
1962 (age 53–54)
Rozenburg, Nederland
Nationality Dutch
Fields
Institutions European Bioinformatics Institute
University of Upsala
Alma mater University of Utrecht
Thesis Computer-assisted assignment of 2D and 3D NMR spectra of proteins (Computer-ondersteunde toekenning van 2D en 3D NMR spectra van eiwitten) (1991)
Website
http://www.ebi.ac.uk/about/people/gerard-kleywegt

Gerard Jacob Kleywegt (born 5 June 1962, Rozenburg) is a Dutch X-ray crystallographer and the team leader of the Protein Data Bank in Europe at the EBI;[1][2][3] a member of the Worldwide Protein Data Bank.[4][5]

Education

Kleywegt obtained his PhD from the University of Utrecht in 1991.

Career

After his PhD, Kleywegt did postdoctoral research with Alwyn Jones at Uppsala University.[6][7] before moving to the EBI.

Research

Kleywegt's research focuses on protein crystallography[8][9][10] and the Protein Data Bank.[11][12][13][14][15][16][17]

References

  1. ↑ "Gerard Kleywegt research group page at the EBI". Archived from the original on 2014-10-20.
  2. ↑ Garwoord, Jeremy (May 2009) "A Guardian of Structural Integrity". Lab Times. pp. 19-23
  3. ↑ Berman, H. M.; Kleywegt, G. J.; Nakamura, H.; Markley, J. L.; Burley, S. K. (2010). "Safeguarding the integrity of protein archive". Nature. 463 (7280): 425. doi:10.1038/463425c.
  4. ↑ Lewis, T. E.; Sillitoe, I; Andreeva, A; Blundell, T. L.; Buchan, D. W.; Chothia, C; Cozzetto, D; Dana, J. M.; Filippis, I; Gough, J; Jones, D. T.; Kelley, L. A.; Kleywegt, G. J.; Minneci, F; Mistry, J; Murzin, A. G.; Ochoa-Montaño, B; Oates, M. E.; Punta, M; Rackham, O. J.; Stahlhacke, J; Sternberg, M. J.; Velankar, S; Orengo, C (2015). "Genome3D: Exploiting structure to help users understand their sequences". Nucleic Acids Research. 43 (Database issue): D382–6. doi:10.1093/nar/gku973. PMID 25348407.
  5. ↑ Lewis, T. E.; Sillitoe, I; Andreeva, A; Blundell, T. L.; Buchan, D. W.; Chothia, C; Cuff, A; Dana, J. M.; Filippis, I; Gough, J; Hunter, S; Jones, D. T.; Kelley, L. A.; Kleywegt, G. J.; Minneci, F; Mitchell, A; Murzin, A. G.; Ochoa-Montaño, B; Rackham, O. J.; Smith, J; Sternberg, M. J.; Velankar, S; Yeats, C; Orengo, C (2013). "Genome3D: A UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains". Nucleic Acids Research. 41 (Database issue): D499–507. doi:10.1093/nar/gks1266. PMC 3531217Freely accessible. PMID 23203986.
  6. ↑ Jones, T. A.; Kleywegt, G. J. (2007). "Experimental Data for Structure Papers". Science. 317 (5835): 194c. doi:10.1126/science.317.5835.194c.
  7. ↑ Kleywegt, G. J.; Jones, T. A. (1996). "Phi/psi-chology: Ramachandran revisited". Structure (London, England : 1993). 4 (12): 1395–400. doi:10.1016/s0969-2126(96)00147-5. PMID 8994966.
  8. ↑ Read, R. J.; Adams, P. D.; Arendall Wb, 3rd; Brunger, A. T.; Emsley, P; Joosten, R. P.; Kleywegt, G. J.; Krissinel, E. B.; Lütteke, T; Otwinowski, Z; Perrakis, A; Richardson, J. S.; Sheffler, W. H.; Smith, J. L.; Tickle, I. J.; Vriend, G; Zwart, P. H. (2011). "A new generation of crystallographic validation tools for the protein data bank". Structure. 19 (10): 1395–412. doi:10.1016/j.str.2011.08.006. PMC 3195755Freely accessible. PMID 22000512.
  9. ↑ Read, R. J.; Kleywegt, G. J. (2009). "Case-controlled structure validation". Acta Crystallographica Section D. 65 (Pt 2): 140–7. doi:10.1107/S0907444908041085. PMC 2631636Freely accessible. PMID 19171969.
  10. ↑ Kleywegt, G. J.; Read, R. J. (1997). "Not your average density". Structure. 5 (12): 1557–69. doi:10.1016/s0969-2126(97)00305-5. PMID 9438862.
  11. ↑ Montelione, G. T.; Nilges, M; Bax, A; Güntert, P; Herrmann, T; Richardson, J. S.; Schwieters, C. D.; Vranken, W. F.; Vuister, G. W.; Wishart, D. S.; Berman, H. M.; Kleywegt, G. J.; Markley, J. L. (2013). "Recommendations of the wwPDB NMR Validation Task Force". Structure. 21 (9): 1563–70. doi:10.1016/j.str.2013.07.021. PMC 3884077Freely accessible. PMID 24010715.
  12. ↑ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2013). "How community has shaped the Protein Data Bank". Structure. 21 (9): 1485–91. doi:10.1016/j.str.2013.07.010. PMID 24010707.
  13. ↑ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2013). "The future of the protein data bank". Biopolymers. 99 (3): 218–22. doi:10.1002/bip.22132. PMC 3684242Freely accessible. PMID 23023942.
  14. ↑ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2012). "The Protein Data Bank at 40: Reflecting on the past to prepare for the future". Structure. 20 (3): 391–6. doi:10.1016/j.str.2012.01.010. PMC 3501388Freely accessible. PMID 22404998.
  15. ↑ Berman, H. M.; Kleywegt, G. J.; Nakamura, H.; Markley, J. L.; Burley, S. K. (2010). "Safeguarding the integrity of protein archive". Nature. 463 (7280): 425. doi:10.1038/463425c.
  16. ↑ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2014). "The Protein Data Bank archive as an open data resource". Journal of Computer-Aided Molecular Design. 28 (10): 1009–14. doi:10.1007/s10822-014-9770-y. PMC 4196035Freely accessible. PMID 25062767.
  17. ↑ Berman, H. M.; Burley, S. K.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2014). "Response to on prompt update of literature references in the Protein Data Bank". Acta Crystallographica Section D. 70 (Pt 10): 2780. doi:10.1107/S1399004714020513. PMID 25286863.
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