Ferredoxin—nitrate reductase
| ferredoxin—nitrate reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.7.7.2 | ||||||||
| CAS number | 60382-69-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a ferredoxin—nitrate reductase (EC 1.7.7.2) is an enzyme that catalyzes the chemical reaction
- nitrite + H2O + 2 oxidized ferredoxin nitrate + 2 reduced ferredoxin + 2 H+
The 3 substrates of this enzyme are nitrite, H2O, and oxidized ferredoxin, whereas its 3 products are nitrate, reduced ferredoxin, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is nitrite:ferredoxin oxidoreductase. Other names in common use include assimilatory nitrate reductase, nitrate (ferredoxin) reductase, and assimilatory ferredoxin-nitrate reductase. This enzyme participates in nitrogen metabolism. It has 4 cofactors: iron, Sulfur, Molybdenum, and Iron-sulfur.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1PFD.
References
- Mikami B; Ida S (1984). "Purification and properties of ferrodoxin-nitrate reductase from the cyanobacterium Plectonema borganum". Biochim. Biophys. Acta. 791: 294–304. doi:10.1016/0167-4838(84)90340-6.