Methanesulfonate monooxygenase

Methanesulfonate monooxygenase
Identifiers
EC number 1.14.13.111
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Methanesulfonate monooxygenase (EC 1.14.13.111, mesylate monooxygenase, mesylate,reduced-FMN:oxygen oxidoreductase, MsmABCD, methanesulfonic acid monooxygenase, MSA monooxygenase, MSAMO) is an enzyme with systematic name methanesulfonate,NADH:oxygen oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

methanesulfonate + NADH + H+ + O2 formaldehyde + NAD+ + sulfite + H2O

Methanesulfonate monooxygenase is a flavoprotein.

References

  1. de Marco, P.; Moradas-Ferreira, P.; Higgins, T.P.; McDonald, I.; Kenna, E.M.; Murrell, J.C. (1999). "Molecular analysis of a novel methanesulfonic acid monooxygenase from the methylotroph Methylosulfonomonas methylovora". J. Bacteriol. 181 (7): 2244–2251. PMC 93639Freely accessible. PMID 10094704.
  2. Higgins, T.P.; Davey, M.; Trickett, J.; Kelly, D.P.; Murrell, J.C. (1996). "Metabolism of methanesulfonic acid involves a multicomponent monooxygenase enzyme". Microbiology. 142: 251–260. doi:10.1099/13500872-142-2-251. PMID 8932698.
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