Diafiltration
Diafiltration is a dilution process that involves removal or separation of components (permeable molecules like salts, small proteins, solvents etc.,) of a solution based on their molecular size by using micro-molecule permeable filters in order to attain pure solution[1][2][3][4][5][6][7]
References
- ↑ "Optimization of Ultrafiltration/Diafiltration Processes for Partially Bound Impurities". Biotechnology and BioEngineering. Wiley Online Library.
- ↑ Blatt, W.F.; Robinson, S.M.; Bixler, Harris J. (Oct 1968). "Membrane ultrafiltration: The diafiltration technique and its application to microsolute exchange and binding phenomena". Analytical Biochemistry. Elsevier. pp. 151–173.
- ↑ Schwartz, Larry. "Diafiltration: A Fast, Efficient Method for Desalting, or Buffer Exchange of Biological Samples". Literature library. Pall Corporation.
- ↑ "Protein Concentration and Diafiltration by Tangential Flow Filtration" (PDF). Millipore.
- ↑ Sweeney, Scott F.; Woehrle, Gerd H.; Hutchison, James E. (2006). "Rapid Purification and Size Separation of Gold Nanoparticles via Diafiltration". Journal of the American Chemical Society. ACS Publications. doi:10.1021/ja0558241.
- ↑ Schwartz, Larry. "Diafiltration for Desalting or Buffer Exchange" (PDF). BioProcess International.
- ↑ "Diafiltration (Buffer Exchange) Using Hollow Fiber Membranes instead of Dialysis Tubing - Automated Diafiltration" (PDF).
Further reading
- Bowen, W. Richard; Mohammad, A. Wahab (Aug 1998). "Diafiltration by nanofiltration: Prediction and optimization". Wiley Online Library; American Institute of Chemical Engineers (AIChE). pp. 1799–1812. doi:10.1002/aic.690440811.
- Limayem, Imène; Charcosset, Catherine; Fessi, Hatem (2004). "Purification of nanoparticle suspensions by a concentration/diafiltration process". Separation and Purification Technology. Elsevier. pp. 1–9.
- Sheth, Jignesh P., et al. "Nanofiltration-based diafiltration process for solvent exchange in pharmaceutical manufacturing." Journal of membrane science 211.2 (2003): 251-261.
External links
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