Corex

For other uses, see Corex (disambiguation).

Corex is a cough syrup sold by Pfizer Inc.. It is available in India, Pakistan, Bangladesh and a few other South Asian countries. Corex is a prescribed medicine.

Its active ingredients are chlorpheniramine maleate and codeine phosphate.

Description

Each 100 ml of Corex Cough Syrup contains:

Alcohol IP 8 mg
Chlorpheniramine Maleate IP 4 mg
Codeine Phosphate IP 10 mg
Carmoisine and Sunset

Mechanism of action

Chlorpheniramine maleate, an H1-blocking antihistamine, relieves histamine-induced allergic edema of respiratory mucosa. Codeine phosphate, by its action on the cough center in the medulla, helps reduce excessive frequency and intensity of cough bouts, which allows the patient to rest or sleep.

Legal status

Legally, Corex can only be obtained by a physician's prescription, but studies show that more than 90% of the product is sold without one.

Corex is not generally a fatal drug substitute, unless taken in extremely high quantities. However, many side effects are common. Corex is known to cause short term memory loss, sleeplessness, tremors and spasms. Muscular pains and dehydration are other common side-effects.

Long term abuse leads to serious kidney damage or constipation. Corex has a high sugar content, and may be unsuitable for acute diabetic patients.

Currently corex has been banned in India.

Cough and cold preparations (R05)

Expectorants

Mucolytics

Cough suppressants

Opium alkaloids, opioids, and derivatives	Acetyldihydrocodeine Benzylmorphine Butorphanol Codeine Dextromethorphan Dihydrocodeine Dimemorfan Droxypropine Ethylmorphine Heroin Hydrocodone Hydromorphone Isoaminile Laudanum Levomethadone Levopropoxyphene Methadone Nicocodeine Nicodicodeine Normethadone Noscapine Pholcodine Thebacon Tipepidine

Other	Benzonatate Benproperine Bibenzonium bromide Butamirate Clobutinol Clofedanol Cloperastine Diphenhydramine Dibunate Dimethoxanate Dropropizine Fedrilate Glaucine Levodropropizine Meprotixol Morclofone Nepinalone Oxolamine Oxeladin Pentoxyverine Pipazetate Prenoxdiazine Piperidione Zipeprol

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