Chemical probe

Not to be confused with Hybridization probe.

Chemical probes are reagents that allow the user to probe into mechanistic and phenotypic questions about their molecular targets. They can rapidly and reversibly inhibit a protein or protein domain in cells.[1] They typically have an extremely high in vitro potency and have very high specificity relative to other proteins of the same family.[2] For more information about chemical probes in general or for specific advice about which chemical probes are most suited to an experiment, visit The Chemical Probes Portal.

References

  1. ↑ "The promise and peril of chemical probes : Nature Chemical Biology : Nature Publishing Group". Nature.com. Retrieved July 27, 2015.
  2. ↑ "Chemical Probes Versus Drugs. In the Pipeline:". Pipeline.corante.com. Retrieved July 27, 2015.
This article is issued from Wikipedia - version of the 11/15/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.