CNOT6
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CCR4-NOT transcription complex subunit 6 is a protein that in humans is encoded by the CNOT6 gene.[3][4]
The protein encoded by this gene is a subunit of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substates.[4]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Chen J, Chiang YC, Denis CL (Mar 2002). "CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase". EMBO J. 21 (6): 1414–26. doi:10.1093/emboj/21.6.1414. PMC 125924
. PMID 11889047. - 1 2 "Entrez Gene: CNOT6 CCR4-NOT transcription complex, subunit 6".
Further reading
- Okubo K, Itoh K, Fukushima A, et al. (1996). "Monitoring cell physiology by expression profiles and discovering cell type-specific genes by compiled expression profiles.". Genomics. 30 (2): 178–86. doi:10.1006/geno.1995.9887. PMID 8586417.
- Nagase T, Ishikawa K, Kikuno R, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (5): 337–45. doi:10.1093/dnares/6.5.337. PMID 10574462.
- Albert TK, Lemaire M, van Berkum NL, et al. (2000). "Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.". Nucleic Acids Res. 28 (3): 809–17. doi:10.1093/nar/28.3.809. PMC 102560. PMID 10637334.
- Dupressoir A, Morel AP, Barbot W, et al. (2003). "Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding.". BMC Genomics. 2: 9. doi:10.1186/1471-2164-2-9. PMC 61044. PMID 11747467.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Chang TC, Yamashita A, Chen CY, et al. (2004). "UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant.". Genes Dev. 18 (16): 2010–23. doi:10.1101/gad.1219104. PMC 514181. PMID 15314026.
- Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer.". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674.
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