CDP-glucose 4,6-dehydratase

CDP-glucose 4,6-dehydratase
Identifiers
EC number 4.2.1.45
CAS number 37259-55-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In the field of enzymology, a CDP-glucose 4,6-dehydratase is an enzyme that catalyzes the chemical reaction

CDP-glucose CDP-4-dehydro-6-deoxy-D-glucose + H2O

Hence, this enzyme has one substrate, CDP-glucose, and two products, CDP-4-dehydro-6-deoxy-D-glucose and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. This enzyme participates in starch and sucrose metabolism. It employs one cofactor, NAD+.

Nomenclature

The systematic name of this enzyme class is CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming). Other names in common use include:

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1RKX and 1WVG.

References


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