Asthma Life Impact Scale

The Asthma Life Impact Scale (ALIS) measure is a disease specific patient reported outcome questionnaire which assesses the impact that asthma has on a patient’s quality of life.[1]

The questionnaire has 22 items,[1] which goes beyond earlier focus on the symptoms, functioning and environmental triggers of asthma and includes emotional issues.[2]

Development

The ALIS was developed simultaneously in the UK and the US via interviews and focus groups.[3] It was developed and published in 2010 by Galen Research and funded by Novartis AG.[1] It was the first asthma specific quality of life measure that was developed using Item Response Theory.[4] Items that were featured on the ALIS include: “asthma restricts my social activities”; “asthma affect my close relationships”, “my illness controls me” and “my asthma affects my interest in sex”.[5]

International use

Currently, the ALIS has been translated into 16 different languages,[6] including Russian and Italian.[4]

References

  1. 1 2 3 Meads, David M.; McKenna, Stephen P.; Doward, Lynda C.; Pokrzywinski, Robin; Revicki, Dennis; Hunter, Cameron; Glendenning, G. Alastair (May 2010). "Development and validation of the Asthma Life Impact Scale (ALIS)". Respiratory Medicine. 104 (5): 633–643. doi:10.1016/j.rmed.2009.11.023. PMID 20053543. Retrieved 14 October 2013.
  2. Shen, Joannie; Johnston, Michael; Hays, Ron D. (2011). "Asthma Outcome Measures" (PDF). Expert Review of Pharmacoeconomics & Outcomes Research. 11 (4): 447–453. doi:10.1586/erp.11.48. Archived from the original (PDF) on 17 October 2013. Retrieved 14 October 2013.
  3. Crawford, S.R.; McKenna, S.; Twiss, J.; Tammaru, M.; Oprandi, N.C. (November 2011). "PRS53 Further Developments of the Asthma Life Impact Scale (ALIS)". Value in Health. 14 (7): A497. doi:10.1016/j.jval.2011.08.1440. Retrieved 14 October 2013.
  4. 1 2 Twiss, J.; McKenna, S.P.; Crawford, S.R.; Tammaru, M.; Oprandi, N.C. (2011). "Adapting the Asthma Life Impact Scale (ALIS) for use in Southern European (Italian) and Eastern European (Russian) cultures". Journal of Medical Economics. 14 (6): 729–738. doi:10.3111/13696998.2011.615356. PMID 21899487. Retrieved 14 October 2013.
  5. Piper, Lucy (11/05/2010). "Asthma Life Impact Scale is 'reliable and valid'". Medwire News. Retrieved 14 October 2013. Check date values in: |date= (help)
  6. Crawford, SR. "Further Developments of the Asthma Life Impact Scale (ALIS)" (PDF). Galen-Research.com. Galen Research. Retrieved 14 October 2013.
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