Alpha-gurjunene synthase

Alpha-gurjunene synthase
Identifiers
EC number 4.2.3.72
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Alpha-gurjunene synthase (EC 4.2.3.72) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((-)-alpha-gurjunene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (-)-alpha-gurjunene + diphosphate

Initial cyclization probably gives biyclogermacrene in an enzyme bound form.

References

  1. Schmidt, C.O.; Bouwmeester, H.J.; Bulow, N.; Konig, W.A. (1999). "Isolation, characterization, and mechanistic studies of (-)-α-gurjunene synthase from Solidago canadensis". Arch. Biochem. Biophys. 364: 167–177. doi:10.1006/abbi.1999.1122. PMID 10190971.

External links

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