Alan Brash (pharmacologist)

Alan Richard Brash (born 1949) is a professor of pharmacology at Vanderbilt University.[1] He is a leading authority on the biosynthesis of prostoglandins and eicosanoids.[1]

Biography

Education

Brash was educated at Strathallan School near Perth, Scotland and Downing College, Cambridge, where he was elected a scholar.[2] He graduated with a BA in medical sciences in 1970 and proceeded to the University of Edinburgh to study for his PhD, graduating in 1976.[3] Brash was then appointed a research fellow in the Department of Clinical Pharmacology at the Royal Postgraduate Medical School in London.[3] Thereafter, he moved to Vanderbilt University.[3]

Research

During his time at Vanderbilt, Brash's research has focused on the analysis of the mechanisms of formation and transformation of lipoxygenase products with an interest in their physiological role.[3] His findings have initiated further research on stereochemical aspects of lipoxygenase catalysis and on the role of epithelial lipoxygenases.[3]

Furthermore, his research has led to more work on the biochemistry of the CYP74 family of cytochrome P450s, and on the catalase-related hemoproteins which also metabolize fatty acid hydroperoxides.[3] As of 2009 he had published almost 200 research papers.[4]

In October 2013 he was elected a Fellow of the American Association for the Advancement of Science.[5]

References

  1. 1 2 "Vanderbilt celebrates 18 elected fellows of the AAAS". Vanderbilt University. 25 November 2013. Retrieved 29 October 2015.
  2. ↑ "A R Brash" (PDF). The Strathallian. Vol. 9 no. 3. Autumn 1970. p. 13. Retrieved 29 October 2015.
  3. 1 2 3 4 5 6 Brash, Alan R (September 2009). "Mechanistic aspects of CYP74 allene oxide synthases and related cytochrome P450 enzymes". Phytochemistry. 70 (13-14): 1522–1531. doi:10.1016/j.phytochem.2009.08.005. PMC 2783490Freely accessible. PMID 19747698.
  4. ↑ List of publications from Microsoft Academic Search
  5. ↑ "AAAS Members Elected as Fellows" (PDF). Science. 29 November 2013. p. 1064. Retrieved 29 October 2015.

External links

Official website

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