3-Succinoylsemialdehyde-pyridine dehydrogenase

3-Succinoylsemialdehyde-pyridine dehydrogenase
Identifiers
EC number 1.2.1.83
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

3-Succinoylsemialdehyde-pyridine dehydrogenase (EC 1.2.1.83) is an enzyme with systematic name 4-oxo-4-(pyridin-3-yl)butanal:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

4-oxo-4-(pyridin-3-yl)butanal + NADP+ + H2O 4-oxo-4-(pyridin-3-yl)butanoate + NADPH + H+

The enzyme has been characterized from the soil bacterium Pseudomonas sp. HZN6.

References

  1. Qiu, J.; Ma, Y.; Wen, Y.; Chen, L.; Wu, L.; Liu, W. (2012). "Functional identification of two novel genes from Pseudomonas sp. strain HZN6 involved in the catabolism of nicotine". Appl. Environ. Microbiol. 78 (7): 2154–2160. doi:10.1128/AEM.07025-11. PMC 3302611Freely accessible. PMID 22267672.

External links

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