3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase

3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase
Identifiers
EC number 4.1.1.51
CAS number 37289-49-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase (EC 4.1.1.51) is an enzyme that catalyzes the chemical reaction

3-hydroxy-2-methylpyridine-4,5-dicarboxylate 3-hydroxy-2-methylpyridine-5-carboxylate + CO2

Hence, this enzyme has one substrate, 3-hydroxy-2-methylpyridine-4,5-dicarboxylate, and two products, 3-hydroxy-2-methylpyridine-5-carboxylate and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase (3-hydroxy-2-methylpyridine-5-carboxylate-forming). This enzyme is also called 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase. This enzyme participates in vitamin B6 metabolism.

References


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