2-hydroxy-1,4-benzoquinone reductase
| 2-hydroxy-1,4-benzoquinone reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.6.5.7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a 2-hydroxy-1,4-benzoquinone reductase (EC 1.6.5.7) is an enzyme that catalyzes the chemical reaction
- 2-hydroxy-1,4-benzoquinone + NADH + H+ 1,2,4-trihydroxybenzene + NAD+
The 3 substrates of this enzyme are 2-hydroxy-1,4-benzoquinone, NADH, and H+, whereas its two products are 1,2,4-trihydroxybenzene and NAD+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a quinone or similar compound as acceptor. The systematic name of this enzyme class is 2-hydroxy-1,4-benzoquinone:NADH oxidoreductase. Other names in common use include hydroxybenzoquinone reductase, 1,2,4-trihydroxybenzene:NAD oxidoreductase, and NADH:2-hydroxy-1,4-benzoquinone oxidoreductase. This enzyme participates in gamma-hexachlorocyclohexane degradation and 1,4-dichlorobenzene degradation.
References
- Chakrabarty AM; Daubaras, DL; Zago, A; Xun, L; Saido, K; Klem, T; Nikolic, D; Chakrabarty, AM (1998). "Novel pathway for conversion of chlorohydroxyquinol to maleylacetate in Burkholderia cepacia AC1100". J. Bacteriol. 180 (17): 4667–75. PMC 107482
. PMID 9721310.